Publications of the University of Nevada, Las Vegas Department of Health Physics & Diagnostic Sciences Faculty.

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Submissions from 2022

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Xrcc4 and mre11 Roles and Transcriptional Response to Repair of Talen-Induced Double-Strand Dna Breaks, Ronald Benjamin, Atoshi Banerjee, Xiaogang Wu, Corey Geurink, Lindsay Buczek, Danielle Eames, Sara G. Trimidal, Janice M. Pluth, and Martin R. Schiller

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Race and Ethnic Group Dependent Space Radiation Cancer Risk Predictions, Francis A. Cucinotta and Premkumar B. Saganti

Submissions from 2021

Carbon Ion Radiotherapy in the Management of Hepatocellular Carcinoma, Belal Abousaida, Danushka Seneviratne, Bradford S. Hoppe, Stephen J. Ko, Aroumougame Asaithamby, Francis A. Cucinotta, Jessica M. Kirwan, Kabir Mody, Beau Toskich, Jonathan B. Ashman, Christopher L. Hallemeier, and Sunil Krishnan

Adequacy of Target Volume Drawn Based On "Slow" CT Scan for SBRT Lung Treatment in Helical TomoTherapy, S. Awan, R. Bakdul, S. Gupta-burt, and Ali Meigooni

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A COVID-19 Risk Score Combining Chest CT Radiomics and Clinical Characteristics to Differentiate COVID-19 Pneumonia From Other Viral Pneumonias, Zuhua Chen, Xiadong Li, Jiawei Li, Shirong Zhang, Pengfei Zhou, Xin Yu, Yao Ren, Jiahao Wang, Lidan Zhang, Yunjiang Li, Baoliang Wu, Yanchun Hou, Ke Zhang, Rongjun Tang, Yongguang Liu, Zhongxian Ding, Bin Yang, Qinghua Deng, Qin Lin, Ke Nie, Zhaobin Cai, Shenglin Ma, and Yu Kuang

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A Proposed Change to Astronaut Exposures Limits Is a Giant Leap Backwards for Radiation Protection, Francis A. Cucinotta, Walter Schimmerling, Eleanor A. Blakely, and Tom K. Hei

Accurate Measurement of Agatston Score Using kVp-Independent Reconstruction Algorithm for Ultra-High-Pitch Sn150 kVp CT, Xi Hu, Xinwei Tao, Yueqiao Zhang, Zhongfeng Niu, Yong Zhang, Thomas Allmendinger, Yu Kuang, and Bin Chen

Prediction of Cardiotoxicity for Breast Cancer Patients Using Light Gradient Boosting Machine, Z. Jiang, P. Diao, Y. Liang, K. Dai, H. Li, H. Wang, Y. Chen, M. Lu, and Yu Kuang

Comparison between PHITS and GEANT4 Simulations of the Heavy Ion Beams at the BEVALAC at LBNL and the Booster Accelerator at BNL, Sungmin Pak and Francis A. Cucinotta

A Preliminary Study of the Organic and Nonorganic Food Ingredients with Instrumental Neutron Activation Analysis, Zaijing Sun

A Study of the Organic and Nonorganic Food Ingredients with Instrumental Neutron Activation Analysis, Zaijing Sun, Yaoling Long, and Qingsheng Cai

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Future Space Missions and Human Enhancement: Medical and Ethical Challenges, Konrad Szocik, Mark Shelhamer, Martin Braddock, Francis A. Cucinotta, Chris Impey, Pete Worden, Ted Peters, Milan M. Ćirković, Kelly C. Smith, Koji Tachibana, Michael J. Reiss, Ziba Norman, Arvin M. Gouw, and Gonzalo Munévar

Study Of Total, Absorption, and 3He and 3H Production Cross Sections in 4He-Proton Collisions, Congchong Yan, Premkumar B. Saganti, and Francis A. Cucinotta

Submissions from 2020

Dosimetric Comparisons of Different Hypofractionated Stereotactic Radiotherapy Techniques in Treating Intracranial Tumors > 3 CM in Longest Diameter, Hongbin Cao, Zhiyan Xiao, Yin Zhang, Tiffany Kwong, Shabbar F. Danish, Joseph Weiner, Xiao Wang, Ning Yue, Zhitao Dai, Yu Kuang, Yongrui Bai, and Ke Nie

Cancer and Circulatory Disease Risks for a Human Mission to Mars: Private Mission Considerations, Francis A. Cucinotta, Eliedonna Cacao, Myung Hee Y. Kim, and Premkumar B. Saganti

A 4DCT Radiomics and Thermography-Based Radiothermomics Model for Early Prediction of Severe Radiation Dermatitis in Patients with Breast Cancer Receiving Radiation Treatment, H. Feng, X. Li, L. Wang, L. Xu, W. Deng, and Yu Kuang

Lack of Supporting Data Make the Risks of a Clinical Trial of Radiation Therapy as a Treatment for COVID-19 Pneumonia Unacceptable, David G. Kirsch, Maximilian Diehn, Francis A. Cucinotta, and Ralph Weichselbaum

Response Letter: Radiation therapy for COVID-19 pneumopathy, David G. Kirsch, Maximilian Diehn, Francis A. Cucinotta, and Ralph Weichselbaum

Analysis Of Key Factors For Radiomic Feature Extraction Stability And Robustness On 4DCT Image, X. Li, Q. Deng, S. Ma, L. Zhang, and Yu Kuang

Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks?, Pataje G. Prasanna, Gayle E. Woloschak, Andrea L. DiCarlo, Jeffrey C. Buchsbaum, Dörthe Schaue, Arnab Chakravarti, Francis A. Cucinotta, Silvia C. Formenti, Chandan Guha, Dale J. Hu, Mohammad K. Khan, David G. Kirsch, Sunil Krishnan, Wolfgang W. Leitner, Brian Marples, William McBride, Minesh P. Mehta, Shahin Rafii, Elad Sharon, Julie M. Sullivan, Ralph R. Weichselbaum, Mansoor M. Ahmed, Bhadrasain Vikram, C. Norman Coleman, and Kathryn D. Held

Temporal Data Mining in Nuclear Site Monitoring and In Situ Decommissioning, Z.J. Sun and A. Duncan

Seeking Frequent Episodes in Baseline Data of in-Situ Decommissioning (ISD) Sensor Network Test Bed With Temporal Data Mining Tools, Z.J. Sun, A. Duncan, Y. Kim, and K. Zeigler

Associations Between Obesity and Metabolic Health With Nonalcoholic Fatty Liver Disease in Elderly Chinese, Li-Ming Wu, Hui He, Gang Chen, Yu Kuang, Bing-Yi Lin, Xin-Hua Chen, and Shu-Sen Zheng

Submissions from 2019

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Meta-Analysis of Cognitive Performance by Novel Object Recognition After Proton and Heavy Ion Exposures, Eliedonna Cacao and Francis A. Cucinotta

Seventeenth International Symposium on Microdosimetry, Roberto Cherubini, Francis A. Cucinotta, and Peter O'Neill

Predictions of Cognitive Detriments from Galactic Cosmic Ray Exposures to Astronauts on Exploration Missions, Francis A. Cucinotta and Eliedonna Cacao

Risks of Conitive Detriments after Low Dose Heavy Ion and Proton Exposures, Francis A. Cucinotta and Eliedonna Cacao

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Response of Human Small Intestinal Epithelium to Fractionated Irradiation: Dynamical Modeling Approach, Francis A. Cucinotta and Olga A. Smirnova

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Nitric Oxide Is Involved in Heavy Ion-Induced Non-Targeted Effects in Human Fibroblasts, Megumi Hada, Premkumar B. Saganti, and Francis A. Cucinotta

Potential of Gd-EOB-DTPA as an Imaging Biomarker for Liver Injury Estimation After Radiation Therapy, Xiao-Li Sun, Xue Jiang, Yu Kuang, Lei Xing, Lu-Yi Bu, Shuang-Hu Yuan, Jin-Ming Yu, and Shu-Sen Zheng

Monte Carlo Computer Simulation of a Camera System for Proton Beam Range Verification in Cancer Treatment, Xiao-Li Sun, Hui Wang, Xin-Ke Li, Guo-Hong Cao, Yu Kuang, and Xiao-Chen Zhang

Applying Instrumental Neutron Activation Analysis (INAA) to the Study of Toxic Elements in Cotton Seeds, Zaijing Sun

An On-Board Spectral-CT/CBCT/SPECT Imaging Configuration for Small-Animal Radiation Therapy Platform: A Monte Carlo Study, Hui Wang, Ke Nie, and Yu Kuang

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Sub-Region Based Radiomics Analysis for Survival Prediction in Oesophageal Tumours Treated by Definitive Concurrent Chemoradiotherapy, Congying Xie, Pengfei Yang, Xuebang Zhang, Lei Xu, Xiaoju Wang, Xiadong Li, Luhan Zhang, Ruifei Xie, Ling Yang, Zhao Jing, Hongfang Zhang, Lingyu Ding, Yu Kuang, Tianye Niu, and Shixiu Wu

Sub-Region Based Radiomics Analysis for Survival Prediction in Esophageal Tumors Treated by Radiotherapy, P. Yang, L. Xu, Z. Cao, Y. Jiang, Y. Xue, C. Luo, Shixiu Wu, Yu Kuang, and Tianye Niu

Submissions from 2018

Biophysics Model of Heavy-Ion Degradation of Neuron Morphology in Mouse Hippocampal Granular Cell Layer Neurons, Murat Alp and Francis A. Cucinotta

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Modeling Reveals the Dependence of Hippocampal Neurogenesis Radiosensitivity on Age and Strain of Rats, Eliedonna Cacao, Sidath Kapukotuwa, and Francis A. Cucinotta

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Stochastic Modeling of Radiation-induced Dendritic Damage on in Silico Mouse Hippocampal Neurons, Eliedonna Cacao, Vipan K. Parihar, Charles L. Limoli, and Francis A. Cucinotta

Cancer and Circulatory Disease Risks for a Human Mission to Mars: Private Mission Considerations, Francis A. Cucinotta, Eliedonna Cacao, Myung-Hee Y. Kim, and Premkumar B. Saganti

Non-Targeted Effects Lead to A Paridigm Shift in Risk Assessment for A Mission to the Earth’s Moon or Martian Moon Phobos, Francis A. Cucinotta, Eliedonna Cacao, Myung-Hee Y. Kim, and Premkumar B. Saganti

Detriments In Neuron Morphology Following Heavy Ion Irradiation: What’s The Target?, Francis A. Cucinotta and Murat Alp Eliedonna Cacao

Pion-heavy Ion Scattering Total and Inelastic Cross Sections for Space Radiation Applications, Francis A. Cucinotta, Myung-Hee Y. Kim, and Premkumar B. Saganti

Dependence of the Human Leukemia Risk on the Dose and Dose Rate of Continuous Irradiation: Modeling Study, Francis A. Cucinotta and Olga A. Smirnova

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Dosimetric Feasibility of 4DCT-ventilation Imaging Guided Proton Therapy for Locally Advanced Non-small-cell Lung Cancer, Qijie Huang, Salma K. Jabbour, Zhiyan Xiao, Ning Yue, Xiao Wang, Hongbin Cao, Yu Kuang, Yin Zhang, and Ke Nie

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A Novel Deep Learning Framework for Internal Gross Target Volume Definition from 4D Computed Tomography of Lung Cancer Patients, Xiadong Li, Ziheng Deng, Qinghua Deng, Lidan Zhang, Tianye Niu, and Yu Kuang

A Radiogenomics Framework to Improve Prediction of Clinical Outcomes in Patients with Esophageal Cancer Treated with Concurrent Chemoradiotherapy, X. Li, P. Yang, Y. Lu, X. J. Wang, Z. Jing, L. Yang, H. Zhang, B. Xia, L. Ding, T. Niu, S. Wu, and Yu Kuang

Limiting Glioma Development By Photodynamic Therapy-generated Macrophage Vaccine And Allo-stimulation: An In Vivo Histological Study In Rats, S J. Madsen, C Christie, K Huynh, Q Peng, F A. Uzal, T B. Krasieva, and H Hirschberg

Variations of Quantitative Perfusion Measurement on Dynamic Contrast Enhanced CT for Colorectal Cancer: Implication of Standardized Image Protocol, Tianye Niu, Pengfei Yang, Xiaonan Sun, Tingyu Mao, Lei Xu, Ning Yue, Yu Kuang, Liming Shi, and Ke Nie

A New Standard DNA Damage (SDD) Data Format, J. Schuemann, A. L. McNamara, J. W. Warmenhoven, N. T. Henthorn, K. J. Kirkby, M. J. Merchant, S. Ingram, H. Paganetti, K. D. Held, J. Ramos-Mendez, B. Faddegon, J. Perl, D. T. Goodhead, I. Plante, H. Rabus, H. Nettelbeck, W. Friedland, P. Kundrát, A. Ottolenghi, G. Baiocco, S. Barbieri, M. Dingfelder, S. Incerti, C. Villagrasa, M. Bueno, M. A. Bernal, S. Guatelli, D. Sakata, J. M. C. Brown, Z. Francis, and I. Kyriakou

Photochemical Internalization Enhanced Macrophage Delivered Chemotherapy, D Shin, C Christie, D Ju, R K. Nair, S Molina, K Berg, T B. Krasieva, S J. Madsen, and H Hirschberg

Genetic Variation and Radiation Quality Impact Cancer Promoting Cellular Phenotypes in Response to HZE Exposure, Deepa M. Sridharan, Shiena Enerio, Chris Wang, Mark A. LaBarge, Martha R. Stampfer, and Janice M. Pluth

First Demonstration of a Prompt Gamma Slit‐Camera for in Vivo Proton Range Verification Based On Semiconductor Detectors, H. Wang, Y. Lu, and Yu Kuang

Submissions from 2017

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Track structure model of microscopic energy deposition by protons and heavy ions in segments of neuronal cell dendrites represented by cylinders or spheres, M Alp and F A. Cucinotta

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Photothermal therapy employing gold nanoparticle-loaded macrophages as delivery vehicles: Comparing the efficiency of nanoshells versus nanorods, C Christie, S J. Madsen, Q Peng, and H Hirschberg

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Non-Targeted Effects Models Predict Significantly Higher Mars Mission Cancer Risk than Targeted Effects Models, F A. Cucinotta and E Cacao

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Predictions of space radiation fatality risk for exploration missions, F A. Cucinotta, K To, and E Cacao

2nd-Order Optical Model of the Isotopic Dependence of Heavy ion Absorption Cross Sections for Radiation Transport Studies, Francis A. Cucinotta, Congchong Yan, and Premkumar B. Saganti

Interpreting Microdosimetry Spectra, John F. Dicello and Francis A. Cucinotta

Charged Particles in Oncology, Marco Durante, Francis A. Cucinotta, and Jay Loeffler

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Editorial: Charged particles in oncology, M Durante, F A. Cucinotta, and J S. Loeffler

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Synergistic efficacy of ultrasound, sonosensitizers and chemotherapy: a review, Henry Hirschberg and Steen J. Madsen

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Advances in Neural Engineering for Rehabilitation, X Hu, T Zhao, J Yao, Y Kuang, and Y Yang

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[18F]Fluorocholine PET/CT Imaging of Liver Cancer: Radiopathologic Correlation with Tissue Phospholipid Profiling, S A. Kwee, M M. Sato, Y Kuang, A Franke, L Custer, K Miyazaki, and L L. Wong

Conebeam CT for Medical Imaging and Image-Guided Interventions, Tianye Niu and Yu Kuang

Dynamical Modeling Approach to Risk Assessment for Radiogenic Leukemia among Astronauts Engaged in Interplanetary Space Missions, Olga Smirnova and Francis A. Cucinotta

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Statistical image-domain multimaterial decomposition for dual-energy CT, Y Xue, R Ruan, X Hu, Y Kuang, J Wang, Y Long, and T Niu

Submissions from 2016

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Modeling Heavy-Ion Impairment of Hippocampal Neurogenesis after Acute and Fractionated Irradiation, Eliedonna Cacao and F A. Cucinotta

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Modeling Impaired Hippocampal Neurogenesis after Radiation Exposure, Elliedonna Cacao and F A. Cucinotta

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Relative biological effectiveness of HZE particles for chromosomal exchanges and other surrogate cancer risk endpoints, Elliedonna Cacao, M Hada, P B. Saganti, K A. George, and F A. Cucinotta

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Harderian gland tumorigenesis: Low-dose and LET response, P Y. Chang, Francis Cucinotta, K A. Bjornstad, J Bakke, C J. Rosen, N Du, D G. Fairchild, E Cacao, and E A. Blakely

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Synergistic Chemotherapy by Combined Moderate Hyperthermia and Photochemical Internalization, Catherine Christie, Stephanie Molina, Jonathan Gonzales, Kristian Berg, Rohit Kumar Nair, Khoi Huynh, Steen J. Madsen, and Henry Hirschberg

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Increasing the efficacy of antitumor glioma vaccines by photodynamic therapy and local injection of allogeneic glioma cells, C E. Christie, Q Peng, Steen Madsen, F A. Uzal, and H Hirschberg

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Space Radiation Quality Factors and the Delta-ray Dose and Dose-Rate Effectiveness Factor, Francis A. Cucinotta, Murat Alp, and Eliedonna Cacao

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No evidence for an increase in circulatory disease mortality in astronauts following space radiation exposures, Francis Cucinotta, N Hamada, and M P. Little

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Focused ultrasound-mediated sonochemical internalization: An alternative to light-based therapies, J Gonzales, R K. Nair, Steen Madsen, T Krasieva, and H Hirschberg

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Cell mediated photothermal therapy of brain tumors, Henry Hirschberg and Steen J. Madsen

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The earlier evaluation of response to neoadjuvant chemoradiation therapy in sarcoma using DCE-MRI, Yu Kuang, W. Xia, L. Chen, and X. Gao

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Photochemical internalisation for solid malignancies, Steen Madsen

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Physics of photodynamic therapy, Steen Madsen

Comparing the effects of light-or sonic-activated drug delivery: Photochemical/sonochemical internalization, Steen Madsen, J Gonzales, G Zamora, K Berg, R K. Nair, and H Hirschberga

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Comparing the Effects of Light or Sonic Activated Drug Delivery: Photo/Sono Chemical Internalization, Steen J. Madsen, Jonathan Gonzales, Genesis Zamora, Kristian Berg, Rohit Kumar Nair, and Henry Hirschberg

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Photothermal enhancement of chemotherapy mediated by gold-silica nanoshell-loaded macrophages: in vitro squamous cell carcinoma study, Steen J. Madsen, En-Chung Shih, Qian Peng, Catherine Christie, Tatiana Krasieva, and Henry Hirschberg

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Skin Response to Single and Fractionated Irradiation: Dynamic Modeling Approach, O A. Smirnova and Francis Cucinotta

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On Determining the Zenith-Angle Dependence of the Martian Radiation Environment at Gale Crater Altitudes, Robert F. Wimmer-Schweingruber, Jan Kohler, Donald J. Hassler, Jingnan Guo, Jan-Kristoffer Appel, Cary Zeitlin, Eckart Bohm Bent, Ehresmann, Henning Lohf, Stephan I. Bottcher Sonke, Burmeister, Cesar Martin, Alexander Kharytonov, David E. Brinza, Arik Posner, Gunther Reitz, Daniel Matthia, Scott Rafkin, Gerald Weigle, and Francis Cucinotta

Submissions from 2015

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Macrophages as Nanoparticle Delivery Vectors for Photothermal Therapy of Brain Tumors., Catherine Christie, Steen J. Madsen, Qian Peng, and Henry Hirschberg

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Determination of Radioisotopes in Complex Saline Matrices using Extraction Chromatography and Liquid Scintillation Counting, Jaimie K. Daum and Ralf Sudowe

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Production and Isolation of Homologs of Flerovium and Element 115 at the Lawrence Livermore National Laboratory Center for Accelerator Mass Spectrometry, John D. Despotopulos, Kelly N. Kmak, Narek Gharibyan, Todd A. Brown, Pat M. Grant, Roger A. Henderson, Ken J. Moody, Scott J. Tumey, Dawn A. Shaughnessy, and Ralf Sudowe

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Broadband detection of dynamic acoustic emission process induced by 6 MV therapeutic X-ray beam from a clinical linear accelerator, Xianfen Diao, Jing Zhu, Weihao Li, Nan Deng, Chien Ting Chin, Xiyuan Zheng, Xinyu Zhang, Xin Chen, Xianming Li, and Yu Kuang

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Macrophage mediated PCI enhanced gene-directed enzyme prodrug therapy, Henry Hirschberg, Kristian Berg, Young J. Kwon, and Steen Madsen

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Ultrasonic irradiation to enhance chemotherapy, Henry Hirschberg, Jonathan Gonzales, Rohit Kumar Nair, and Steen J. Madsen

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Comparison of Two RapidArc Delivery Strategies in Stereotactic Body Radiotherapy of Peripheral Lung Cancer with Flattening Filter Free Beams, Bao-Tian Huang, Jia-Yang Lu, Pei-Xian Lin, Jian-Zhou Chen, Yu Kuang, and Chuang-Zhen Chen

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Volumetric Modulated Arc Therapy Planning for Primary Prostate Cancer With Selective Intraprostatic Boost Determined by 18F-Choline PET/CT, Yu Kuang, Lili Wu, Emily Hirata, Kyle Miyazaki, Miles Sato, and Sandi A. Kwee

18F-NaF PET/CT-directed Dose Escalation in Stereotactic Body Radiation Therapy for Bone Metastases from Prostate Cancer, Yu Kuang, L Wu, S. A. Kwee, M Li, X Peng, L. Xie, and Z. Lin

Fluorine-18 fluorocholine PET/CT reflects CDP-choline metabolism as one of the two major phosphatidylcholine synthesis pathways in the liver, S. A. Kwee, A. Franke, L. Custer, X Li, K. Miyazaki, Yu Kuang, and L. Wong

Histopathology of Lesions Defined by 18F-fluorocholine PET/CT for Radiation Therapy Boost Treatment of Prostate Cancer, S. Kwee, E Hirata, M. Sato, K Miyazaki, L Wu, and Yu Kuang

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Nanoparticle-loaded macrophage-mediated photothermal therapy: potential for glioma treatment, Steen J. Madsen, Seok Jin Hong, Anthony Trinidad, Suyog Chhetri, Qian Peng, Francisco A. Uzal, and Henry Hirschberg

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Efficacy of combined photothermal therapy and chemotherapeutic drugs, Steen Madsen, En-Chung Shih, and Henry Hirschberg

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A Performance Comparison of Commercially Available Strontium Extraction Chromatography Columns, Derek R. McLain, Carol J. Mertz, and Ralf Sudowe

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Changes in Skeletal Tumor Activity on 18F-choline PET/CT in Patients Receiving 223Radium Radionuclide Therapy for Metastatic Prostate Cancer, Kyle S. Miyazaki and Yu Kuang

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18F-NaF PET/CT-Directed Dose Escalation in Stereotactic Body Radiotherapy for Spine Oligometastases from Prostate Cancer, L. Wu, S. A. Kwee, M. Li, X. Peng, L. Xie, Z. Lin, H. Wang, and Yu Kuang