Document Type

Poster

Publication Date

2014

Publisher

University of Nevada, Las Vegas; Center for Academic Enrichment and Outreach

Abstract

The first platinum-based drug was discovered and approved by Food and Drug Administration (FDA) in 1978 is cis-diamminedichloroplatinum (II) (cisplatin or CDDP). Cisplatin is used for about 50% of the chemotherapeutic cancer treatments along with its two analogues carboplatin and oxaliplatin. So far these drugs have been used extensively as treatment for ovarian, bladder, head and neck, and lung cancers. Although cisplatin has been used so often, it has toxic side effects and drug resistance.1-4 Due to these limitations other compounds have been synthesized. Specifically, our lab in conjunction with a biochemistry lab has recently published one article in this area. This project is a continuation to the development of anticancer drugs.

Keywords

Cancer; Cancer--Chemotherapy; Cancer--Treatment; Chemotherapy; Cisplatin

Disciplines

Biochemistry | Biochemistry, Biophysics, and Structural Biology | Cancer Biology | Life Sciences

Language

English


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