Title
Relationship of Mitochondrial Enzymes to Fatigue Intensity in Men With Prostate Cancer Receiving External Beam Radiation Therapy
Document Type
Article
Publication Date
5-1-2016
Publication Title
Biological Research for Nursing
Volume
18
Issue
3
First page number:
274
Last page number:
280
Abstract
Mitochondrial dysfunction is a plausible biological mechanism for cancer-related fatigue. Specific aims of this study were to (1) describe the levels of mitochondrial oxidative phosphorylation complex (MOPC) enzymes, fatigue, and health-related quality of life (HRQOL) before and at completion of external beam radiation therapy (EBRT) in men with nonmetastatic prostate cancer (PC); (2) examine relationships over time among levels of MOPC enzymes, fatigue, and HRQOL; and (3) compare levels of MOPC enzymes in men with clinically significant and nonsignificant fatigue intensification during EBRT.
Disciplines
Nursing
Repository Citation
Filler, K.,
Lyon, D.,
McCain, N.,
Bennett, J.,
Fernández-Martínez, J. L.,
deAndrés-Galiana, E. J.,
Elswick, R. K.,
Lukkahatai, N.,
Saligan, L.
(2016).
Relationship of Mitochondrial Enzymes to Fatigue Intensity in Men With Prostate Cancer Receiving External Beam Radiation Therapy.
Biological Research for Nursing, 18(3),
274-280.
http://dx.doi.org/10.1177/1099800415617848