Title

Tag Team Ubiquitin Ligases

Document Type

Article

Publication Date

1-1-2016

Publication Title

Cell

Volume

166

Issue

5

First page number:

1080

Last page number:

1081

Abstract

Cullin-RING (CRL) and RING1-IBR-RING2 (RBR) are two distinct types of ubiquitin ligases. In this issue, Scott et al. show that CRLs activate the RBR enzyme ARIH1 to initiate ubiquitin chains on CRL substrates, thereby marking an unexpected and important advance in our understanding of both enzymes. © 2016 Elsevier Inc.

Language

English

UNLV article access

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