Title

Development of LEU-Based Targets for Radiopharmaceutical Manufacturing: A Review

Document Type

Article

Publication Date

3-18-2019

Publication Title

Applied Radiation and Isotopes

Volume

148

First page number:

225

Last page number:

231

Abstract

99Mo is an essential medical isotope that comprises of at least 70% of radioactive procedures globally. Currently an essential component of 99Mo manufacturing is the uranium target from which 99Mo is produced by fission. As the world moves towards low enriched uranium (LEU) targets due to non-proliferation concerns it is becoming of interest to find methods to increase the efficiency of the LEU targets in order to reduce the ever increasing nuclear waste levels of which a long term solution for disposal or treatment has yet to be satisfactorily found. Advantages and disadvantages of various target designs are investigated and discussed along current disposal and reprocessing methods. The idea of a reusable target is introduced as a way forward in reducing the nuclear waste burden for future generations.

Disciplines

Medicinal-Pharmaceutical Chemistry | Radiochemistry

Language

English

UNLV article access

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