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To identify risk factors for the occurrence of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men, we conducted a case-control study in New York City, San Francisco, Los Angeles, and Atlanta. Fifty patients (cases) (39 with Kaposi's sarcoma, 8 with pneumocystis pneumonia, and 3 with both) and 120 matched homosexual male controls (from sexually transmitted disease clinics and private medical practices) participated in the study. The variable most strongly associated with illness was a larger number of male sex partners per year (median, 61 for patients; 27 and 25 for clinic and private practice controls, respectively). Compared with controls, cases were also more likely to have been exposed to feces during sex, have had syphilis and non-B hepatitis, have been treated for enteric parasites, and have used various illicit substances. Certain aspects of a lifestyle shared by a subgroup of the male homosexual population are associated with an increased risk of Kaposi's sarcoma and pneumocystis pneumonia.


Epidemiology; Gay men; Kaposi's sarcoma – Risk factors; Pneumocystis carinii pneumonia – Risk factors


Community Health and Preventive Medicine | Epidemiology | Immune System Diseases | Public Health | Virus Diseases


Posted in the UNLV Institutional Repository with the permission of the American College of Physicians (ACP), all rights reserved. Copies are for personal use only; this material may not be re-posted. The ACP encourages users to go to the original article on the Annals of Internal Medicine website for scientific integrity, in the event there are retractions and corrections.

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