The National Gonorrhea Therapy Monitoring Study: II. Trends and Seasonality of Antibiotic Resistance of Neisseria Gonorrhoeae

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THE GONORRHEA THERAPY Monitoring Study was designed to monitor the efficacy of therapy of gonorrhea and the antibiotic susceptibility of isolates of Neisseria gonorrhoeae in vitro, and to correlate characteristics of patients and gonococcal isolates with rates of therapeutic failure. Since November 1972, isolates of N. gonorrhoeae have been collected from study patients before treatment and tested in vitro for susceptibilities to penicillin, ampicillin, tetracycline, and spectinomycin. Since 1974, some isolates have also been tested in vitro for susceptibility to amoxicillin; since 1975, to erythromycin and trimethoprimsulfamethoxazole (TMP-SMZ); since 1976, to cefoxitin. The purpose of this report is to describe recent trends of resistance and to examine the seasonality of resistance of N. gonorrhoeae to antibiotics.


Antibiotics; Drug resistance in microorganisms; Gonorrhea – Treatment


Analytical, Diagnostic and Therapeutic Techniques and Equipment | Diseases | Female Urogenital Diseases and Pregnancy Complications | Male Urogenital Diseases | Pharmaceutics and Drug Design


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