Quadrivalent Meningococcal Vaccine Uptake Among Men Who Have Sex With Men During a Meningococcal Outbreak in Los Angeles County, California, 2016-2017

Authors

Ian W. Holloway, University of California, Los Angeles
Elizabeth S. C. Wu, University of California, Los Angeles
Jennifer Gildner, 2RAND Corporation
Vincent L. Fenimore, Emory University
Diane Tan, University of California, Los Angeles
Laura Randall, Emory University
Paula M. Frew, University of Nevada, Las VegasFollow

Document Type

Article

Publication Date

9-6-2018

Publication Title

Public Health Reports

Volume

133

Issue

5

First page number:

559

Last page number:

569

Abstract

Objective: The objective of our study was to assess meningococcal ACWY (MenACWY) vaccine uptake among men who have sex with men (MSM) during an ongoing, invasive meningococcal disease outbreak in Southern California. This research was important to inform future vaccination uptake interventions for this high-priority population. Methods: We conducted venue-based sampling to recruit and enroll MSM living in Los Angeles County, California, from December 2016 through February 2017. We conducted bivariate and multivariable analyses to evaluate associations between MenACWY vaccine uptake and other predetermined factors. Results: Of 368 participants, 138 (37.5%) reported receiving the MenACWY vaccine. In multivariable analyses, older age (adjusted odds ratio [aOR] = 2.57; 95% confidence interval [CI], 1.31-5.03), previous diagnosis of a sexually transmitted infection (aOR = 2.22; 95% CI, 1.14-4.30), belief that MenACWY vaccine is important (aOR = 3.49; 95% CI, 1.79-6.82), confidence in the MenACWY vaccine (aOR = 5.53; 95% CI, 3.11-9.83), and knowing someone who had been vaccinated (aOR = 5.82; 95% CI, 3.05-11.12) were significantly associated with MenACWY vaccine uptake. Conclusions: Our findings reflect low uptake of the recommended MenACWY vaccine among MSM after a local outbreak, despite public health efforts. In addition to ongoing, widespread campaigns to inform MSM about local outbreaks and vaccination recommendations, MSM may be responsive to direct outreach from peers who have been vaccinated.

Keywords

Meningococcal; Meningitis; Quadrivalent meningococcal vaccine; MenACWY; MSM; Vaccine measurement; Immunization acceptance; Immunization assessment

Disciplines

Community Health and Preventive Medicine | Public Health

Language

English

Repository Citation

Holloway, I. W., Wu, E. S., Gildner, J., Fenimore, V. L., Tan, D., Randall, L., Frew, P. M. (2018). Quadrivalent Meningococcal Vaccine Uptake Among Men Who Have Sex With Men During a Meningococcal Outbreak in Los Angeles County, California, 2016-2017. Public Health Reports, 133(5), 559-569.
http://dx.doi.org/10.1177/0033354918781085