Document Type

Article

Publication Date

2011

Publication Title

Physical Review E - Statistical, Nonlinear, and Soft Matter Physics

Volume

84

Issue

2

First page number:

021910-1

Last page number:

021910-6

Abstract

A continuum model is developed to predict the dielectrophoretic polarizability of coiled DNA molecules under the action of an alternating current electric field. The model approximates the coiled DNA molecule as a charged porous spherical particle. The model explains the discrepancies among scaling laws of polarizability of different-sized DNA molecules with contour length and such discrepancies are attributed to different hydrodynamic behavior. With zero or one fitting parameter, theoretical predictions are in good agreement with various experimental data, even though in experiments there are some uncertainties in regard to certain parameters.

Keywords

Dielectrophoresis; DNA; Electric currents; Alternating; Electric fields; Polarization (Electricity)

Disciplines

Biomedical Engineering and Bioengineering | Electrical and Computer Engineering | Mechanical Engineering | Molecular Genetics

Language

English

Permissions

Copyright American Physical Society used with permission.

Identifier

DOI: 10.1103/PhysRevE.84.021910

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