Title

Spatial patterns of fiber types in atrophied skeletal muscle

Document Type

Article

Publication Date

2-1995

Publication Title

Western Journal of Nursing

Volume

17

Issue

1

First page number:

49

Last page number:

62

Abstract

This study examined the spatial distributions of different fiber types in the soleus muscle of control rats and in rats subjected to hindlimb unloading for 28 days. The frequencies with which muscle fibers of one type were adjacent to each other and to fibers of other types were tabulated and compared to expectations generated from Monte Carlo simulations. In the normal rat, there is a tendency for Type I fibers to avoid adjacency with each other, a tendency that persisted in the hindlimb-suspended group, despite the substantial shrinkage in size of Type I fibers. We conclude that this treatment, unlike neurogenic pathologies, does not cause any remodeling of the adjacency relations of fibers.

Keywords

Animals; Disease Models; Animal; Female; Immobilization/adverse effects; Monte Carlo Method; Muscle Fibers; Skeletal/pathology; Muscle; Skeletal/pathology; Muscles – Wounds and injuries; Muscular atrophy; Muscular Atrophy/etiology; Muscular Atrophy/pathology; Random Allocation; Rats; Rats – Wounds and injuries; Rats; Wistar

Disciplines

Medicine and Health Sciences | Nursing

Language

English

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