Role of Puberty and Ovarian Hormones in the Genetic Diathesis of Eating Disorders in Females
Document Type
Article
Publication Date
7-10-2019
Publication Title
Child and Adolescent Psychiatric Clinics of North America
Abstract
Puberty is a critical risk period for eating disorders (EDs). ED incidence increases across the pubertal period and becomes female predominant, and genetic influences on disordered eating significantly increase. Surges of ovarian hormones, particularly estrogen, may drive this increasing genetic effect for EDs in pubertal girls and contribute to differential phenotypic presentations beyond puberty. In this article, we explain phenotypic associations between puberty and disordered eating and present evidence showing underlying genetic and hormonal influence. Potential benefits of communicating roles of genetic influence to people with or at risk for EDs are also discussed.
Keywords
Puberty; Eating disorders; Anorexia nervosa; Bulimia nervosa; Binge eating disorder; Binge eating; Progesterone; Estrogen
Disciplines
Developmental Psychology | Hormones, Hormone Substitutes, and Hormone Antagonists
Language
English
Repository Citation
Ma, R.,
Mikhail, M. E.,
Fowler, N.,
Culbert, K. M.,
Klump, K. L.
(2019).
Role of Puberty and Ovarian Hormones in the Genetic Diathesis of Eating Disorders in Females.
Child and Adolescent Psychiatric Clinics of North America
http://dx.doi.org/10.1016/j.chc.2019.05.008