Mild Acute Inflammation does not Impair Maintenance of Blood Pressure during a Hypotensive Stimulus
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Severe acute inflammation, such as sepsis, disrupts autonomic nervous system function and jeopardizes blood pressure regulation . Acute hypotension under normal conditions stimulates baroreceptors to restore blood pressure by activating the sympathetic nervous system to increase heart rate and vasoconstrict peripheral vasculature. Severe acute experimental inflammation (endotoxin) blunts baroreflex-mediated increases in muscle sympathetic nerve activity during reductions in blood pressure and uncouples baroreflex control of heart rate . Whether mild acute inflammation alters the ability to maintain blood pressure during a hypotensive challenge is less clear.
Acute inflammation; Blood pressure; Blood flow; LBNP
Cardiovascular Diseases | Diseases | Medicine and Health Sciences
Schroeder, E. C.,
Hilgenkamp, T. I.,
Lefferts, W. K.,
Mild Acute Inflammation does not Impair Maintenance of Blood Pressure during a Hypotensive Stimulus.
Artery Research, 26(3),