Award Date

1-1-2001

Degree Type

Thesis

Degree Name

Master of Science (MS)

Department

Kinesiology

First Committee Member

Lawrence Golding

Number of Pages

111

Abstract

Most governing sports authorities have banned the use of anabolic steroids as ergogenic aids. Recently, a transdermal testosterone precursor dietary supplement (AndrosteDERMRTM) has become available; athletes can apply the cream to their skin with the belief that it will increase serum testosterone levels, muscle mass, and strength. The purpose of this study was to measure the effects of one milliliter of AndrosteDERMRTM) applied to the inner surface of the upper arm on the serum levels of androstenedione, and free and total testosterone in female subjects. Serum levels were measured before application and every 45 minutes thereafter for six hours. Serum androstenedione, and free and total testosterone levels were analyzed using radioimmunoassay. Although the trend seemed to indicate that serum levels did not rise after application, several subjects had physiologically impossible values, which appear to be due to methodological errors. That information, along with the initial small number of subjects made the use of statistical treatment unwise and inferences about the population impossible.

Keywords

Acute; Administration; Effects; Females; Hormone; Levels; Precursors; Serum; Steroid; Testosterone; Transdermal

Controlled Subject

Pharmacology; Nutrition

File Format

pdf

File Size

2508.8 KB

Degree Grantor

University of Nevada, Las Vegas

Language

English

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