Title

Adolescent Seizure in the Emergency Department Due to Concomitant Brugada Syndrome

Document Type

Article

Publication Date

8-1-2018

Publication Title

Pediatric Emergency Care

Volume

34

Issue

8

First page number:

E144

Last page number:

E146

Abstract

Brugada syndrome is an inherited sodium channelopathy that often presents with sudden cardiac death in young adult males secondary to ventricular dysrhythmias.1,2 This syndrome is thought to be responsible for 4% to 12% of all sudden deaths and approximately 20% of cardiac-related deaths in patients with structurally normal hearts, although recent studies suggest that the prevalence of Brugada syndrome in these types of death may be lower.3–5 Three variants exist, with only type 1 being diagnostic of Brugada syndrome. The characteristic type 1 electrocardiographic pattern includes J-wave accentuation with associated “coved” ST-segment elevation in the precordial leads, predisposing an affected individual to ventricular arrhythmias. Brugada syndrome has, over the last several years, become a more frequently discussed topic, with much of the literature focusing on the adult population. Despite the fact that the first 2 cases recognized by the Brugada brothers in 1986 were siblings aged 2 and 3 years, there has since been little published on this entity in the pediatric emergency literature.6–10 There are even fewer reported cases of Brugada syndrome manifesting with symptoms other than cardiac arrest or syncope. This case report discusses the presentation, evaluation, and management of a 15-year-old patient presenting with first-time seizure who was diagnosed with Brugada syndrome based on electrocardiogram (ECG) findings.

Keywords

Arrhythmia; Brugada syndrome; Ion channel; Seizure

Disciplines

Emergency Medicine

Language

English

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