Title
Randomized Double-Blinded Comparison of Titrated Oral Versus Vaginal Misoprostol for Labor Induction [24N]
Document Type
Article
Publication Date
4-29-2018
Publication Title
Obstetrics and Gynecology
Volume
131
Issue
p
First page number:
158S
Abstract
INTRODUCTION: For labor induction of an unfavorable cervix, we propose oral misoprostol, titrated to uterine response, to maximize safety and efficacy, based upon past studies. METHODS: Randomized double-blinded study. Identically appearing oral and vaginal study dosages were prepared containing either 25mcg misoprostol or placebo. The pharmacist randomized the study participants to receive either an “oral packet” (oral misoprostol, vaginal placebo) or a “vaginal packet” (opposite). Patients received both an oral protocol (quantity of capsules titrated to uterine contractions, every 2hrs) and vaginal protocol (25mcg/placebo every 4hrs) simultaneously. Providers and patients were blinded. (see full text for full abstract)
Disciplines
Obstetrics and Gynecology
Language
English
Repository Citation
Kennel, P.,
Fu, J.,
Frisch, D.,
Hom, K.,
Allen, H.,
Matsunaga-Kirgan, M.
(2018).
Randomized Double-Blinded Comparison of Titrated Oral Versus Vaginal Misoprostol for Labor Induction [24N].
Obstetrics and Gynecology, 131(p),
158S.
http://dx.doi.org/10.1097/01.AOG.0000533120.72041.a7