Effect of Intrauterine Marijuana Exposure on Fetal Growth Patterns and Placental Vascular Resistance

Bobby K. Brar, University of Nevada, Las Vegas
Pooja S. Patil, University of Nevada, Las Vegas
David N. Jackson, University of Nevada, Las Vegas
Michael O. Gardner, University of Nevada, Las Vegas
James M. Alexander, University of Nevada, Las Vegas
Nora M. Doyle, University of Nevada, Las Vegas

Abstract

Objective: The recent legalization of marijuana has increased overall use, including in pregnancy. Studies have previously associated marijuana use with adverse fetal neurodevelopmental outcomes. We sought to compare fetal sonographic growth parameters and placental perfusion, as measured by umbilical artery Dopplers, in women using daily marijuana versus nonusers. Methods: A retrospective cohort study capturing self – identified pregnant daily marijuana users with gestational aged matched controls was performed. We compared maternal demographics, fetal biometry, nuchal translucency, and umbilical artery Dopplers in marijuana users versus controls. Intrauterine growth restriction was defined as an estimated fetal weight... (see full abstract in article).