Isolated Vascular Rings in the Era of High Prenatal Detection Rates: Demographics, Diagnosis, Risk Factors, and Outcome
Journal of Cardiac Surgery
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© 2021 Wiley Periodicals LLC Objective: We reviewed our center's isolated vascular ring data. Methods: Inclusion criteria were patients born in Nevada between June 2015 and July 2020 with situs solitus, levocardia, atrioventricular and ventriculoarterial concordance, and no significant intracardiac malformations. Results: We identified 95 patients. Of the 95, 56 (59%) were female (p =.033). For the study period, there were approximately 180,000 live births, for a prevalence of 5.3 isolated vascular rings per 10,000 live births. Of the 95, 78 (82%) were prenatally diagnosed. Of the 95, 63 (66%) were products of high-risk pregnancies (p =.0001). Additionally, we found advanced maternal age was an isolated vascular ring risk factor (relative risk ratio, 2.7; 95% confidence interval, 1.8, 4.1; p <.00001). Conclusions: Isolated vascular rings are relatively common cardiovascular malformations and more common in females. High prenatal detection rates are achievable. Further, the majority with isolated vascular rings are products of high-risk pregnancies, and advanced maternal age is a statistically significant occurrence risk factor.
Advanced maternal age; Prenatal diagnosis; Risk factors; Vascular ring
Obstetrics and Gynecology | Pediatrics
Isolated Vascular Rings in the Era of High Prenatal Detection Rates: Demographics, Diagnosis, Risk Factors, and Outcome.
Journal of Cardiac Surgery, 36(4),