Document Type
Article
Publication Date
5-20-2022
Publication Title
Journal of Pediatric Surgery Case Reports
First page number:
1
Last page number:
7
Abstract
Hepatic mesenchymal hamartomas (HMH) are benign liver lesions that present as cystic, slow growing masses within the first few years of life. Few cases demonstrate placental abnormalities and abnormal levels of alpha-fetoprotein (AFP). We report an unusual case of a rapidly growing HMH with associated placental anomalies and elevated AFP. A 2-month-old female born prematurely due to concerning placental findings presented with a prenatally-identified liver mass. Magnetic resonance imaging (MRI) showed a marked increase in the size of the mass over a three- month period. Prior to surgery, the AFP was elevated and decreased after operative resection. Histopathology confirmed the diagnosis HMH. Rapid growth of HMH is not commonly reported and raises concerns for malignancy. Abnormal placental findings may lead to prematurity, which can affect surgical management. We identified 27 cases of prenatally diagnosed HMH since 1983. The mean gestational age for identification was 29 weeks, with the majority managed by delayed resection. The timing for surgical intervention lacks consensus, but malnutrition and perioperative complications should be considered. High AFP levels with an infantile hepatic mass may indicate a more malignant process but does not exclude HMH.
Keywords
Hepatic mesenchymal hamartoma; benign liver tumor; rapid growth
Disciplines
Medical Anatomy | Surgery
File Format
File Size
1700 KB
Language
English
Rights
IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Repository Citation
Bauzon, J.,
Morris, D.,
Hill, C. S.,
Schanda, T.,
Scheidler, M.,
Chang, S.
(2022).
A Rapidly Growing Mesenchymal Hamartoma in a Neonate With Known Placental Anomalies.
Journal of Pediatric Surgery Case Reports
1-7.
Available at:
http://dx.doi.org/10.1016/j.epsc.2022.102324
