Award Date

5-1-2024

Degree Type

Dissertation

Degree Name

Doctor of Medical Physics (DMP)

Department

Health Physics and Diagnostic Sciences

First Committee Member

Steen Madsen

Second Committee Member

Yu Kuang

Third Committee Member

Cephas Mubata

Fourth Committee Member

David Zhang

Fifth Committee Member

Ryan Hecox

Sixth Committee Member

James Navalta

Number of Pages

64

Abstract

Spatially Fractionated Radiation Therapy (SFRT) is a treatment method that distributes a non-uniform dose with alternating peaks and valleys within a tumor. It is an effective technique to treat large and bulky tumors with limited toxicity to surrounding Organs At Risk (OAR), which is normally hard to treat using traditional radiation therapy methods. It can either be delivered by using a three-dimensional conformal planning technique (either physical block or virtually using Multi Leaf Collimators (MLC)), or by Lattice Radiation Therapy (LRT) using Volumetric Modulated Arc Therapy (VMAT) technique. The scope of this work is to compare and implement SFRT treatment techniques at Intermountain Cancer Center (ICC). This requires the investigation of physical and dosimetric characteristics of the grid, describing its clinical implementation and verification, creating treatment plans on test patients using different methods of SFRT, assessment of the parameters that decides the acceptability of the plan, establishing Quality Assurance (QA) methods, and making recommendations about treatment planning and dose reporting. All the measurement results for SFRT commissioning were found to be within clinically acceptable agreement for implementation at ICC.

Keywords

Grid; Intermountain cancer center; Lattice radiation therapy; SFRT; Spatially fractionated

Disciplines

Medicine and Health Sciences

File Format

pdf

File Size

8700 KB

Degree Grantor

University of Nevada, Las Vegas

Language

English

Rights

IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/

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