Study Of The Upper Airway Of Obstructive Sleep Apnea Patient Using Fluid Structure Interaction
Document Type
Article
Publication Date
1-1-2018
Publication Title
Respiratory Physiology and Neurobiology
Publisher
Elsevier B.V.
Volume
249
First page number:
54
Last page number:
61
Abstract
Up to 14% of the U.S. population is estimated to have obstructive sleep apnea (OSA), while the outcomes of the treatments have variable results. In the current study, a three-dimensional fluid-structure interaction modeling was applied to simulate the upper airway to identify the precise location, severity, and characteristic of airway collapse. This was accomplished using Simpleware® and ANSYS® software applied to a 3-D rendering of the airway in a real patient with severe OSA. During this simulation, areas which are prone to collapse and precipitate apneic episodes were identified at the tip of the soft palate and the base of the tongue, with intrathoracic pressure as low as −1370 Pa. These results are consistent with anatomical structures currently indicated and targeted in the treatment of OSA. This improved FSI modeling simulation, which is the first to completely model the whole upper airway without consideration of the nasal cavity in OSA, and can allow virtual modification of the airway prior to actual treatment by doctors. © 2018 Elsevier B.V.
Keywords
Computational fluid dynamics; Fluid-structure interaction; Obstructive sleep apnea; Simulation; Upper airway
Language
English
Repository Citation
Liu, Y.,
Mitchell, J.,
Chen, Y.,
Yim, W.,
Chu, W.,
Wang, R. C.
(2018).
Study Of The Upper Airway Of Obstructive Sleep Apnea Patient Using Fluid Structure Interaction.
Respiratory Physiology and Neurobiology, 249
54-61.
Elsevier B.V..
http://dx.doi.org/10.1016/j.resp.2018.01.005