Location
University of Nevada Las Vegas, Science and Education Building
Start Date
9-8-2011 10:15 AM
End Date
9-8-2011 12:00 PM
Description
Wood frogs (Rana sylvatica) are able to withstand freezing. Respiratory and cardiac activity ceases when frozen. Homeostatic functions like protein synthesis and degradation presumably must also be compromised. We investigated the fate of ubiquitin-dependent proteolysis in the freeze-thaw cycle and how that might gives clues to wood frog survival. We performed western blots for ubiquitin conjugates
Keywords
Cryobiology; Proteins — Metabolism; Rana sylvatica; Wood frog – Hibernation
Disciplines
Animal Sciences | Biochemistry | Cell and Developmental Biology
Language
English
COinS
Ubiquitylation of proteins in the frozen wood frog
University of Nevada Las Vegas, Science and Education Building
Wood frogs (Rana sylvatica) are able to withstand freezing. Respiratory and cardiac activity ceases when frozen. Homeostatic functions like protein synthesis and degradation presumably must also be compromised. We investigated the fate of ubiquitin-dependent proteolysis in the freeze-thaw cycle and how that might gives clues to wood frog survival. We performed western blots for ubiquitin conjugates