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Description

Much research efforts have been centered towards the synthesis of novel Bronsted acid catalysts. These organocatalyst enable synthesis of natural products, pharmaceuticals, and bioactive small molecules under toxic-metal-free conditions by donating their protons, while not being consumed in the reaction. Chiral phosphorothioic acid have significant potential as novel organocatalysts due to their high modifiability of chirality and acidity under environmentally friendly conditions; however, synthesis of these organocatalysts are far and in between. Therefore, our research aimed to i) synthesize novel phosphorothioic acid organocatalysts and ii) to apply these novel catalysts toward new methodology development.

Publisher Location

Las Vegas (Nev.)

Publication Date

12-9-2022

Publisher

University of Nevada, Las Vegas

Language

English

Controlled Subject

Chemistry;Biochemistry

Disciplines

Catalysis and Reaction Engineering | Pharmacology, Toxicology and Environmental Health

File Format

pdf

File Size

478 KB

Comments

Faculty Mentor: Jun Yong Kang

Rights

IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/

Synthesis of Novel Chiral Phosphorothioic Acid Organocatalysts and Application to Synthetic Methodology


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