Effects of cytokines on CNS cells: Glia
Editors
Richard M. Ransohoff; Etty N. Benveniste
Document Type
Chapter
Publication Date
2-16-1996
Publication Title
Cytokines and the CNS
Publisher
CRC Press
Publisher Location
Boca Raton, FL
First page number:
151
Last page number:
168
Abstract
Glial cells act as supportive and homeostatic cells for other glia and neurons in the CNS. However, glia are highly responsive to constituents of the local milieu, and their function is therefore subject to modulation by local factors, some of which may be cytokines. The specific effects of cytokines on glial cells include induction of cytokine production, regulation, and death. This chapter will describe studies that have examined how interferons, tumor necrosis factor, interleukins, colony stimulating factors, and transforming growth factor-βs, affect these properties of microglia, astrocytes, and oligodendrocytes. Rather than review the entire field over the last decade, only the most recent additions to the literature will be discussed.
Keywords
Astrocytes; Cytokines; Neuroglia
Disciplines
Medicine and Health Sciences | Nursing
Language
English
Repository Citation
Schneider, B. S.,
Merrill, J. E.,
Dopp, J. M.
(1996).
Effects of cytokines on CNS cells: Glia. In Richard M. Ransohoff; Etty N. Benveniste,
Cytokines and the CNS
151-168.
Boca Raton, FL: CRC Press.
http://dx.doi.org/10.1016/j.neuron.2009.09.002