Minimotif Miner: A Computational Tool to Investigate Protein Function, Disease, and Genetic Diversity

Editors

John E. Cooligan; Ben M. Dunn; David W. Speicher; Paul T. Wingfield; Gwen P. Taylor

Document Type

Article

Publication Date

5-2007

Publication Title

Current Protocols in Protein Science

Abstract

The Minimotif Miner Web site contains information on several hundred short functional motifs in a single database, and allows the user to search protein queries for the presence of these motifs. Scoring based on evolutionary conservation, protein surface prediction, and motif frequency can be used in conjunction with other motif programs and the known biology of the query to reduce false-positive predictions and select short motifs for experimental pursuit.

Keywords

Biology – Computer network resources; Disease; Evolution; Molecular; Proteins – Structure; Proteins/genetics; Proteins/physiology

Disciplines

Diseases | Ecology and Evolutionary Biology | Genetics and Genomics | Molecular Biology | Physiology

Language

English

Find It

UNLV article access

Search your library

Share

COinS