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H.pylori; diabetes; health disparities; Mexican Americans; Blacks
Epidemiology | Nutritional and Metabolic Diseases | Public Health
Background: In the US, the percentage of adults with diagnosed diabetes are higher in members of racial and ethnic minority groups compared to non-Latino Whites. Understanding why such disparities exist has been less forthcoming.
Methods: Secondary data analysis was conducted using the National Health and Nutrition Examination Survey (NHANES) 1999-2000 cross-sectional data.
Results: H.pylori seropositivity was highest in Mexican Americans (43.7%), lowest in non-Hispanic Whites (18.1%). Diabetes was highest in non-Hispanic Blacks (5.9%); lowest in non-Hispanic whites (4.3%). H.pylori seropositivity was associated with greater likelihood of having type 2 diabetes (1.927, 95% CI 1.142, 3.257) compared to H.pylori negative in unadjusted model. After adjustment, H.pylori seropositivity was no longer associated with diabetes. Obesity (aOR 4.94, 95% CI 2.672,9.133) was associated with having type 2 diabetes compared to normal weight. Non-Hispanic Blacks (2.436, 95% CI 1.489,3.984) and Mexican Americans (1.896, 95% CI 1.002,3.587) had greater odds of diabetes compared to Whites. For nearly all stratified analyses, H.pylori did not have a significant association with type 2 diabetes although several other noteworthy findings emerged. A chance finding, where H.pylori was associated with greater likelihood of diabetes in Mexican Americans, 60-85, >25 BMI, may be worth a closer look.
Conclusion: Findings indicate weight status, obesity in particular, is the strongest predictor of diabetes followed by Black race. Stratified analyses suggest increasing racial disparities over the course of the life span.
Chaidez, Virginia and Qiu, Yumou
"Exploring H.pylori seropositivity as a risk factor for type 2 diabetes,"
Journal of Health Disparities Research and Practice: Vol. 11:
2, Article 4.
Available at: https://digitalscholarship.unlv.edu/jhdrp/vol11/iss2/4