Minimotif Miner (MnM) consists of a minimotif database and a web-based application that enables prediction of motif-based functions in user-supplied protein queries. We have revised MnM by expanding the database more than 10-fold to approximately 5000 motifs and standardized the motif function definitions. The web-application user interface has been redeveloped with new features including improved navigation, screencast-driven help, support for alias names and expanded SNP analysis. A sample analysis of prion shows how MnM 2 can be used.
Amino Acid Motifs/genetics; Databases; Protein; Genetic polymorphisms; Internet; Minimotif Miner; Polymorphism; Single Nucleotide; Prions; Protein Interaction Domains and Motifs; Protein-protein interactions; Sequence Analysis; Protein; User-Computer Interface; User interfaces (Computer systems); Web applications
Biology | Computer Sciences | Life Sciences | Molecular Biology | Structural Biology
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Gradie, P. R.,
Gryk, M. R.,
Maciejewski, M. W.,
Schiller, M. R.
Minimotif miner 2nd release: a database and web system for motif search.
Nucleic Acids Research, 37(Database Issue),