National Surveillance for Neonatal Herpes Simplex Virus Infections

Document Type

Article

Publication Date

1989

Publication Title

Sexually Transmitted Diseases

Issue

16

First page number:

152

Last page number:

156

Abstract

To explore the magnitude and descriptive epidemiology of neonatal herpes simplex virus (HSV) infection, the Centers for Disease Control (CDC) conducted an 18-month hospital-based surveillance study in which 184 cases were reported. Only 22% of mothers had a history of genital HSV infection and only 9% had genital lesions at the time of delivery. Cesarean delivery initiated prior to membrane rupture failed to prevent infection in the 15 cases. These data confirm previous observations that most mothers of infected neonates have no history of genital HSV and are asymptomatic at delivery. Furthermore this study suggests that intrauterine infection may be an important route of transmission and underscores the limitations of current prevention strategy.

Keywords

Herpes simplex virus – Transmission; Newborn infants

Disciplines

Analytical, Diagnostic and Therapeutic Techniques and Equipment | Epidemiology | Obstetrics and Gynecology | Public Health | Virus Diseases

Language

English

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