Document Type

Article

Publication Date

1996

Publication Title

Public Health Reports

Volume

111

First page number:

335

Last page number:

341

Abstract

In the United States, nearly all new human immunodeficiency virus (HIV) infections in children are acquired through perinatal (mother-to-infant) transmission. Each year, approximately 7000 infants are born to HIV-infected women in the United States.1 Without intervention, an estimated 15-30% of these infants would become infected.2 In 1994, results of the AIDS Clinical Trial Group (ACTG) Protocol 076 showed that treatment of infected pregnant women and their infants with zidovudine (ZDV) reduced the rate of perinatal HIV transmission from 25% to 8%.3,4 Following these findings, the Public Health Service (PHS) issued recommendations for ZDV therapy to prevent perinatal HIV transmission5 and for HIV counseling and voluntary testing of pregnant women.6

Keywords

AIDS (Disease) – Prevention; AIDS (Disease) in pregnancy; HIV infections – Prevention; HIV infections – Transmission; HIV-positive children

Disciplines

Analytical, Diagnostic and Therapeutic Techniques and Equipment | Immune System Diseases | Maternal and Child Health | Obstetrics and Gynecology | Public Health | Virus Diseases

Language

English


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