"Biofilm-Induced Profiles of Immune Response Gene Expression by Oral Ep" by Jeffrey L. Ebersole, Rebecca Peyyala et al.
 

Biofilm-Induced Profiles of Immune Response Gene Expression by Oral Epithelial Cells

Document Type

Article

Publication Date

1-16-2019

Publication Title

Molecular Oral Microbiology

Volume

34

Issue

1

First page number:

1

Last page number:

12

Abstract

his study examined the oral epithelial immunotranscriptome response patterns modulated by oral bacterial planktonic or biofilm challenge. We assessed gene expression patterns when epithelial cells were challenged with a multispecies biofilm composed of Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis representing a type of periodontopathic biofilm compared to challenge with the same species of planktonic bacteria. Of the 579 human immunology genes, a substantial signal of the epithelial cells was observed to 181 genes...(See full text for complete abstract)

Disciplines

Medicine and Health Sciences

Language

English

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