Title
Biofilm-Induced Profiles of Immune Response Gene Expression by Oral Epithelial Cells
Document Type
Article
Publication Date
1-16-2019
Publication Title
Molecular Oral Microbiology
Volume
34
Issue
1
First page number:
1
Last page number:
12
Abstract
his study examined the oral epithelial immunotranscriptome response patterns modulated by oral bacterial planktonic or biofilm challenge. We assessed gene expression patterns when epithelial cells were challenged with a multispecies biofilm composed of Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis representing a type of periodontopathic biofilm compared to challenge with the same species of planktonic bacteria. Of the 579 human immunology genes, a substantial signal of the epithelial cells was observed to 181 genes...(See full text for complete abstract)
Disciplines
Medicine and Health Sciences
Language
English
Repository Citation
Ebersole, J. L.,
Peyyala, R.,
Gonzalez, O. A.
(2019).
Biofilm-Induced Profiles of Immune Response Gene Expression by Oral Epithelial Cells.
Molecular Oral Microbiology, 34(1),
1-12.
http://dx.doi.org/10.1111/omi.12251