Synthesis and Characterization of Novel Calcium Phosphate Glass-Derived Cements for Vital Pulp Therapy

Authors

Jerry Howard, University of UtahFollow
Levi Gardner, University of Utah
Zahra Saifee, University of Utah
Aladdin Geleil, White Engineering Surfaces Corporation
Isaac Nelson, University of Utah
John S. Colombo, University of Nevada, Las VegasFollow
Steven E. Naleway, University of Utah
Krista Carlson, University of UtahFollow

Document Type

Article

Publication Date

1-2-2020

Publication Title

Journal of Materials Science: Materials in Medicine

Volume

31

Issue

1

First page number:

1

Last page number:

12

Abstract

Evaluation of the physicochemical behavior and setting reactions of a novel inorganic pulp capping cement which makes use of the unique corrosion properties of sodium metasilicate (NaSi) glass. NaSi and calcium phosphate (CaP) glass powders were synthesized through a melt-quench method. Cements were created by mixing various amounts of the glasses with deionized water at a powder-to-liquid ratio of 2.5 g mL−1. Working and setting times were measured using the indentation standard ISO 9917-1. Sealing ability was tested by placing set samples of each composition in methylene blue dye solution for 24 h. Set samples were also submerged in phosphate buffered saline and incubated at 37 °C for one week. X-ray diffraction was used to identify mature crystalline phases after incubation. Infrared spectroscopy and scanning electron microscopy were used to characterize cements before and after setting and after incubation. Working and setting times measured in the ranges of 2–5 and 10–25 min, respectively. Working and setting time generally decrease with increased NaSi concentration. Cements with compositions of 25 and 33 wt% NaSi were found to resist the infiltration of dye and maintain their shape. Compositions outside this range absorbed dye and collapsed. Infrared spectroscopy provided insight into the setting mechanism of these cements. After one week in vitro, cements were found to contain crystalline phases matching chemically stable, bioactive phases. The combination of NaSi and CaP glasses has favorable setting behavior, sealing ability, and mature phases for pulp capping while relying on a relatively simple, inorganic composition.

Disciplines

Dental Materials

Language

English

Repository Citation

Howard, J., Gardner, L., Saifee, Z., Geleil, A., Nelson, I., Colombo, J. S., Naleway, S. E., Carlson, K. (2020). Synthesis and Characterization of Novel Calcium Phosphate Glass-Derived Cements for Vital Pulp Therapy. Journal of Materials Science: Materials in Medicine, 31(1), 1-12.
http://dx.doi.org/10.1007/s10856-019-6352-5