Impact of Periodontal Disease on Outcomes in Diabetes

Authors

Kenneth Izuora, University of Nevada School of MedicineFollow
Echezona Ezeanolue, University of Nevada, Las VegasFollow
Karen Schlauch, University of Nevada, Reno
Michael Neubauer, University of Nevada, Las VegasFollow
Civon Gewelber, University of Nevada, Las VegasFollow
Guillermo Umpierrez, Emory UniversityFollow

Document Type

Article

Publication Date

3-1-2015

Publication Title

Contemporary Clinical Trials

Volume

41

First page number:

93

Last page number:

99

Abstract

The prevalence of periodontal disease (POD) among adults aged 30years and older in the United States is reported to be more than 47%, with higher prevalence seen among patients with diabetes mellitus (DM). POD has been associated with systemic inflammation, a known risk factor for cardiovascular and bone disease, both of which are more common in patients with DM. However, there is mixed evidence that treatment of POD reduces inflammation, improves DM control, and reduces DM complications. Our study objectives are to assess factors associated with POD in patients with DM and determine the impact of POD treatment on inflammation and bone turnover biomarkers associated with complications of DM.

Keywords

Bone turnover biomarkers; Diabetes complications; Glycemic control; Inflammation biomarkers; Periodontal disease

Repository Citation

Izuora, K., Ezeanolue, E., Schlauch, K., Neubauer, M., Gewelber, C., Umpierrez, G. (2015). Impact of Periodontal Disease on Outcomes in Diabetes. Contemporary Clinical Trials, 41 93-99.
http://dx.doi.org/10.1016/j.cct.2015.01.011