Comparison of Clinical & Laboratory Standards Institute standards in antimicrobial susceptibility among the carbapenemase producing Enterobacteriaceae

Document Type

Article

Publication Date

10-5-2017

Publication Title

FUTURE SCIENCE OA

Volume

3

Issue

4

First page number:

8

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) are a family of bacteria that can result in deadly infections because they are resistant to most antibiotics. We obtained 54 Klebsiella pneumonia carbapenemase isolates, a type of CRE, and determined which antibiotics were effective against them. Results showed that five isolates that were considered susceptible to an antibiotic under the previous criteria were now considered nonsusceptible with the current standards. This study shows that the current criteria may not offer additional benefits in the fight against CRE infections. Studies such as this one and prudent use of antibiotics should limit the spread of antibiotic resistance.

Keywords

Antibiotics, Antimicrobial stewardship, Carbapenem, Carbapenem resistance, Clinical and Laboratory Standards Institute, Klebsiella pneumoniae

Language

eng

UNLV article access

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