Document Type

Article

Publication Date

9-1-2010

Publication Title

Open Access Journal of Clinical Trials

Publisher

Dove Medical Press

Volume

2010

Issue

2

First page number:

149

Last page number:

156

Abstract

Objective This study examines whether men-who-have-sex-with-men (MSM) and transgender (TG) persons’ attitudes, beliefs, and risk perceptions toward human immunodeficiency virus (HIV) vaccine research have been altered as a result of the negative findings from a phase 2B HIV vaccine study. Design We conducted a cross-sectional survey among MSM and TG persons (N = 176) recruited from community settings in Atlanta from 2007 to 2008. The first group was recruited during an active phase 2B HIV vaccine trial in which a candidate vaccine was being evaluated (the “Step Study”), and the second group was recruited after product futility was widely reported in the media. Methods Descriptive statistics, t tests, and chi-square tests were conducted to ascertain differences between the groups, and ordinal logistic regressions examined the influences of the above-mentioned factors on a critical outcome, future HIV vaccine study participation. The ordinal regression outcomes evaluated the influences on disinclination, neutrality, and inclination to study participation. Results Behavioral outcomes such as future recruitment, event attendance, study promotion, and community mobilization did not reveal any differences in participants’ intentions between the groups. … See full text for complete abstract.

Keywords

AIDS; Men-who-have-sex-with-men; Recruitment; Community engagement; Willingness to participate

Disciplines

Health Services Research | Immunology of Infectious Disease | Lesbian, Gay, Bisexual, and Transgender Studies | Virology

File Format

pdf

File Size

316 KB

Language

English

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

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