PCR Monitoring of Parasitemia during Drug Treatment for Canine Chagas Disease
Document Type
Article
Publication Date
8-5-2019
Publication Title
Journal of Veterinary Diagnostic Investigation
First page number:
1
Last page number:
5
Abstract
To date, there is no clear standard to monitor drug treatment for canine Chagas disease. We used 2 real-time PCR (rtPCR) assays targeting Trypanosoma cruzi kinetoplast DNA (kDNA) and nuclear satellite DNA (nDNA) to detect T. cruzi in canine whole blood. Samples were collected randomly from 131 untreated dogs with unknown T. cruzi infection status in Texas. ... See full text for complete abstract.
Keywords
Canine Changas disease; Kinetoplast DNA; Nuclear satellite DNA; Real-time PCR; Trypanosoma cruzi
Disciplines
Veterinary Infectious Diseases
Language
English
Repository Citation
Zao, C.,
Yang, Y.,
Tomanek, L.,
Cooke, A.,
Berger, R.,
Chien, L.,
Madigan, R.
(2019).
PCR Monitoring of Parasitemia during Drug Treatment for Canine Chagas Disease.
Journal of Veterinary Diagnostic Investigation
1-5.
http://dx.doi.org/10.1177/1040638719868508