Document Type
Article
Publication Date
1-8-2024
Publication Title
Bioengineering
Volume
11
Issue
1
First page number:
1
Last page number:
16
Abstract
Many colonic surgeries include colorectal anastomoses whose leaks may be life-threatening, affecting thousands of patients annually. Various studies propose that mechanical interaction between the staples and neighboring tissues may play an important role in anastomotic leakage. Therefore, understanding the mechanical behavior of colorectal tissue is essential to characterizing the reasons for this type of failure. So far, experimental data characterizing the mechanical properties of colorectal tissue have been few and inconsistent, which has significantly limited understanding their behavior. This research proposes an approach to developing an anisotropic hyperelastic material model for colorectal tissues based on uniaxial testing of freshly harvested porcine specimens, which were collected from several age- and weight-matched pigs. The specimens were extracted from the same colon tract of each pig along their circumferential and longitudinal orientations. We propose a constitutive model combining Yeoh isotropic hyperelastic material with fibers oriented in two directions to account for the hyperelastic and anisotropic nature of colorectal tissues. Experimental data were used to accurately determine the model’s coefficients (circumferential, R2 = 0.9968; longitudinal, R2 = 0.9675). The results show that the proposed model can be incorporated into a finite element model that can simulate procedures such as colorectal anastomoses reliably.
Keywords
colorectal tissues; soft tissue modeling; experimental characterization
Disciplines
Analytical, Diagnostic and Therapeutic Techniques and Equipment | Biomedical Engineering and Bioengineering | Tissues
File Format
File Size
8400 KB
Language
English
Rights
IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Repository Citation
Fahmy, Y.,
Trabia, M. B.,
Ward, B.,
Gallup, L.,
Froehlich, M.
(2024).
Development of an Anisotropic Hyperelastic Material Model for Porcine Colorectal Tissues.
Bioengineering, 11(1),
1-16.
http://dx.doi.org/10.3390/bioengineering11010064
Included in
Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons, Biomedical Engineering and Bioengineering Commons, Tissues Commons