Physical Activity and Peak Oxygen Consumption Are Associated With Walking in Multiple Sclerosis
Document Type
Article
Publication Date
1-9-2020
Publication Title
Multiple Sclerosis and Related Disorders
Volume
40
First page number:
1
Last page number:
5
Abstract
Introduction: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with a prevalence of nearly 1 million adults in the United States. MS results in declines in physical activity and peak oxygen consumption that might be independently associated with declines in walking performance. Therefore our purpose was to evaluate the association between physical activity and peak oxygen consumption with walking performance in individuals with MS. Methods: Fifty individuals with MS between the ages of 18–70 yrs. (Female: 38; 46 ± 12 yrs.; BMI: 28.5 ± 6.4; EDSS: 3.3 [IQR: 2.5–4]) performed a maximal incremental cycle test to assess peak oxygen consumption (VO2peak), and wore an accelerometer for one week to measure moderate-to-vigorous physical activity (MVPA). Subjects further completed a timed 25-foot walk test (T25FW) and 6-minute walk (6MW) to measure walking performance. Results: MVPA and VO2peak were correlated with 6MW and T25FW... (See article for full abstract).
Keywords
Fitness; Mobility; Special populations; Assessment
Disciplines
Immune System Diseases | Physical Therapy
Language
English
Repository Citation
Hibner, B. A.,
Hilgenkamp, T. I.,
Schroeder, E. C.,
Motl, R. W.,
Bollaert, R. E.,
Griffith, G.,
Grigoriadis, G.,
Barynard, T.,
Fernhall, B.
(2020).
Physical Activity and Peak Oxygen Consumption Are Associated With Walking in Multiple Sclerosis.
Multiple Sclerosis and Related Disorders, 40
1-5.
http://dx.doi.org/10.1016/j.msard.2020.101941