BK Virus Nephropathy: Prevalence, Impact and Management Strategies

Authors

Rajeev Sharma, University of Nevada, Las Vegas
Mareena Zachariah, Wayne State University

Document Type

Article

Publication Date

8-7-2020

Publication Title

International Journal of Nephrology and Renovascular Disease

Volume

13

First page number:

1

Last page number:

6

Abstract

BK virus reactivation as a result of therapeutic immunosuppression following renal transplant can result in BK polyomavirus nephropathy and renal allograft loss. This is a complex and challenging clinical problem with a range of management options and practices reported in literature. The current standard for early diagnosis and treatment is surveillance by measuring viral DNA in blood using qPCR. Immunosuppression reduction is the cornerstone of effective management but is associated with a risk of acute rejection following treatment.

Keywords

BK Polyomavirus Nephropathy; Kidney Transplant; Immune Monitoring; Treatment; Surveillance

Disciplines

Medical Specialties | Medicine and Health Sciences | Nephrology

File Format

pdf

File Size

616 KB

Language

English

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

Repository Citation

Sharma, R., Zachariah, M. (2020). BK Virus Nephropathy: Prevalence, Impact and Management Strategies. International Journal of Nephrology and Renovascular Disease, 13 1-6.
http://dx.doi.org/10.2147/IJNRD.S236556