Title

BK Virus Nephropathy: Prevalence, Impact and Management Strategies

Document Type

Article

Publication Date

8-7-2020

Publication Title

International Journal of Nephrology and Renovascular Disease

Volume

13

First page number:

1

Last page number:

6

Abstract

BK virus reactivation as a result of therapeutic immunosuppression following renal transplant can result in BK polyomavirus nephropathy and renal allograft loss. This is a complex and challenging clinical problem with a range of management options and practices reported in literature. The current standard for early diagnosis and treatment is surveillance by measuring viral DNA in blood using qPCR. Immunosuppression reduction is the cornerstone of effective management but is associated with a risk of acute rejection following treatment.

Keywords

BK Polyomavirus Nephropathy; Kidney Transplant; Immune Monitoring; Treatment; Surveillance

Disciplines

Medical Specialties | Medicine and Health Sciences | Nephrology

Language

English

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