Award Date


Degree Type


Degree Name

Doctor of Physical Therapy (DPT)


Physical Therapy

Advisor 1

Merrill Landers

First Committee Member

Merrill Landers

Second Committee Member

Robbin Hickman

Number of Pages



Background: The purpose of this systematic review was to examine effectiveness of land-based exercise interventions for improving quality of life (QOL) of individuals with symptomatic knee osteoarthritis.

Methods: A systematic search included PubMed, CINAHL, Scopus, Academic Search Premier, and the Cochrane Database of Systematic Reviews. Inclusion criteria included land-based exercise interventions aimed to improve lower extremity strength and QOL, published since 2000. Exclusion criteria included OA of joints other than the knee, and aquatic-based and surgical interventions. Studies were evaluated using a modified version of the American Academy of Cerebral Palsy and Developmental Medicine (AACPDM) methodology score.

Results: Level of evidence for 11 studies ranged from I strong (I-S) to IV. There were 1200 total participants 57.5 to 69.8 years of age with a mean of 64.5. Three common treatment groups were used; exercise, yoga, and education. Twenty outcome measures were used with the Western Ontario and McMaster Universities Arthritis Index (WOMAC), Short Form 36 (SF-36) and strength being most common.

Discussion: Inconsistencies in reporting outcome measures and their subgroups, data, and statistical analyses prevented further data analysis to compare individual intervention effectiveness. However, many articles reported significant improvements in varying QOL subgroups and strength measurements.

Conclusions: This review suggests treatment approaches involving physical activity will be beneficial across all levels of the International Classification of Functioning Disability and Health (ICF), including QOL.


Exercise; Knee – Diseases; Osteoarthritis; Physical therapy; Quality of life


Kinesiotherapy | Physical Therapy | Rehabilitation and Therapy

File Format


File Size

809 Kb

Degree Grantor

University of Nevada, Las Vegas




IN COPYRIGHT. For more information about this rights statement, please visit