Master of Science (MS)
First Committee Member
Second Committee Member
Third Committee Member
Fourth Committee Member
Number of Pages
Early childhood caries is one of the most prevalent diseases in the United States among children. The formation of caries is a complex, multifactorial process that is still being studied. Researchers have thought for years that Streptococcus mutans was the primary causative agent of early childhood caries. The recent discovery of a novel cariogenic pathogen, Scardovia wiggsiae and its significant contribution to the etiology of early childhood caries has led oral health researchers to re-evaluate this microorganism and its link to this disease. While there have been several projects undertaken within the University of Nevada, Las Vegas School of Dental Medicine (UNLV SDM), the majority of them have analyzed the overall prevalence in saliva amongst different categories of our clinic population.To date, no studies at UNLV SDM have sought to determine the precise location of S. wiggsiae in the oral cavity amongst those patients harboring this bacterium. The purpose of this study was to determine where in the oral cavity, if any, S. wiggiae primarily resides. This may shed light on the best prophylactic means of reducing the risk for S. wiggiae induced ECC. Sample collection during this study was performed using paper points in multiple sites within the oral cavity, evaluating both hard and soft tissues. A DNA quality and quantitative evaluation was also performed on all samples collected, to determine the efficacy of paper point sample collection in our dental clinic in hopes to pave way for this technique to be used in future studies within the UNLV SDM.
Dental; Dentistry; oral; Scardovia; Scardovia wiggsiae; Wiggsiae
Epidemiology | Microbiology | Pathology
University of Nevada, Las Vegas
Carr, Graydon Ramos, "Oral Localization of Scardovia Wiggsiae" (2020). UNLV Theses, Dissertations, Professional Papers, and Capstones. 3871.
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