PK11195 Increases Anxiety Like Behaviors in the Open Field

Authors

Audrey Donald, University of Nevada, Las VegasFollow
Dustin Hines, University of Nevada, Las VegasFollow

Funder

Center for Academic Enrichment and Outreach

Document Type

Poster

Publication Date

1-1-2017

Publisher

University of Nevada, Las Vegas; Center for Academic Enrichment and Outreach

Publisher Location

Las Vegas (Nev.)

Abstract

Anxiety is one of the most common mental illnesses in the US. Signaling between regions of the brain can be corrupted causing stress related behaviors. Medications that help treat these behaviors target GABA receptors in an inhibitory manner. However, these medications only work for a period of time. The likelihood of being free of these medications becomes uncertain. Another approach is a protein called translocator protein. TSPO, once known as peripheral benzodiazepine receptor is known to mediate anxiety related behaviors through the synthesis of neurosteriods. While TSPO may mediate these behaviors, its mechanism is not well known. Ligand PK11195 was used to evaluate behaviors in animal models using the open field task.

Keywords

Anxiety behaviors; PK11195

Disciplines

Clinical Psychology

File Format

pdf

File Size

211 KB

Language

English

Rights

IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/

Repository Citation

Donald, A., Hines, D. (2017). PK11195 Increases Anxiety Like Behaviors in the Open Field.
Available at: https://digitalscholarship.unlv.edu/aanapisi_posters/39