E2F Transcription Factor 1 and its Role in the Cell Cycle and Tumor Suppressor Proteins

Authors

Thea Hisuler, University of Nevada, Las VegasFollow
Yu Kuang, University of Nevada, Las VegasFollow

Funder

Center for Academic Enrichment and Outreach

Document Type

Poster

Publication Date

1-1-2017

Publisher

University of Nevada, Las Vegas; Center for Academic Enrichment and Outreach

Publisher Location

Las Vegas (Nev.)

Abstract

E2F Transcription Factor 1 (E2F1) E2F1 is a transcription factor, in which its expression is increased in human cancers. “Transcription factor E2F1 binds to and activates transcription,” in return leading to increased transcription at the G1 and S phase of the cell cycle (Slansky). The E2F transcription factor family “plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses” (NCBI).

Keywords

Tumor suppressor proteins; E2F1; Cancer

Disciplines

Analytical, Diagnostic and Therapeutic Techniques and Equipment

File Format

pdf

File Size

1.645 KB

Language

English

Rights

IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/

Repository Citation

Hisuler, T., Kuang, Y. (2017). E2F Transcription Factor 1 and its Role in the Cell Cycle and Tumor Suppressor Proteins.
Available at: https://digitalscholarship.unlv.edu/aanapisi_posters/40