University of Nevada, Las Vegas; Center for Academic Enrichment and Outreach
E2F Transcription Factor 1 (E2F1) E2F1 is a transcription factor, in which its expression is increased in human cancers. “Transcription factor E2F1 binds to and activates transcription,” in return leading to increased transcription at the G1 and S phase of the cell cycle (Slansky). The E2F transcription factor family “plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses” (NCBI).
Tumor suppressor proteins; E2F1; Cancer
Analytical, Diagnostic and Therapeutic Techniques and Equipment
E2F Transcription Factor 1 and its Role in the Cell Cycle and Tumor Suppressor Proteins.
Available at: https://digitalscholarship.unlv.edu/aanapisi_posters/40