Tag Team Ubiquitin Ligases
Document Type
Article
Publication Date
1-1-2016
Publication Title
Cell
Volume
166
Issue
5
First page number:
1080
Last page number:
1081
Abstract
Cullin-RING (CRL) and RING1-IBR-RING2 (RBR) are two distinct types of ubiquitin ligases. In this issue, Scott et al. show that CRLs activate the RBR enzyme ARIH1 to initiate ubiquitin chains on CRL substrates, thereby marking an unexpected and important advance in our understanding of both enzymes. © 2016 Elsevier Inc.
Language
English
Repository Citation
Kleiger, G.,
Deshaies, R.
(2016).
Tag Team Ubiquitin Ligases.
Cell, 166(5),
1080-1081.
http://dx.doi.org/10.1016/j.cell.2016.08.014