Development of LEU-Based Targets for Radiopharmaceutical Manufacturing: A Review
Document Type
Article
Publication Date
3-18-2019
Publication Title
Applied Radiation and Isotopes
Volume
148
First page number:
225
Last page number:
231
Abstract
99Mo is an essential medical isotope that comprises of at least 70% of radioactive procedures globally. Currently an essential component of 99Mo manufacturing is the uranium target from which 99Mo is produced by fission. As the world moves towards low enriched uranium (LEU) targets due to non-proliferation concerns it is becoming of interest to find methods to increase the efficiency of the LEU targets in order to reduce the ever increasing nuclear waste levels of which a long term solution for disposal or treatment has yet to be satisfactorily found. Advantages and disadvantages of various target designs are investigated and discussed along current disposal and reprocessing methods. The idea of a reusable target is introduced as a way forward in reducing the nuclear waste burden for future generations.
Disciplines
Medicinal-Pharmaceutical Chemistry | Radiochemistry
Language
English
Repository Citation
Raposio, R.,
Thorogood, G.,
Czerwinski, K.,
Rozenfield, A.
(2019).
Development of LEU-Based Targets for Radiopharmaceutical Manufacturing: A Review.
Applied Radiation and Isotopes, 148
225-231.
http://dx.doi.org/10.1016/j.apradiso.2019.03.019