Production and Supply of A-Particle-Emitting Radionuclides for Targeted A-Therapy
Document Type
Article
Publication Date
11-1-2021
Publication Title
Journal of Nuclear Medicine
Volume
62
Issue
11
First page number:
1495
Last page number:
1503
Abstract
Encouraging results from targeted a-therapy have received significant attention from academia and industry. However, the limited availability of suitable radionuclides has hampered widespread translation and application. In the present review,we discuss themost promising candidates for clinical application and the state of the art of their production and supply. In this review, along with 2 forthcoming reviews on chelation and clinical application of a-emitting radionuclides, The Journal of Nuclear Medicine will provide a comprehensive assessment of the field.
Keywords
211At; 212Pb/212Bi; 225Ac/213Bi; 227Th/223Ra; Production and supply of radionuclides; Targeted a-therapy
Disciplines
Nuclear | Radiochemistry
Repository Citation
Radchenko, V.,
Morgenstern, A.,
Jalilian, A.,
Ramogida, C.,
Cutler, C.,
Duchemin, C.,
Hoehr, C.,
Haddad, F.,
Bruchertseifer, F.,
Gausemel, H.,
Yang, H.,
Osso, J.,
Washiyama, K.,
Czerwinski, K.,
Leufgen, K.,
Pruszynski, M.
(2021).
Production and Supply of A-Particle-Emitting Radionuclides for Targeted A-Therapy.
Journal of Nuclear Medicine, 62(11),
1495-1503.
http://dx.doi.org/10.2967/jnumed.120.261016