Title

Production and Supply of A-Particle-Emitting Radionuclides for Targeted A-Therapy

Document Type

Article

Publication Date

11-1-2021

Publication Title

Journal of Nuclear Medicine

Volume

62

Issue

11

First page number:

1495

Last page number:

1503

Abstract

Encouraging results from targeted a-therapy have received significant attention from academia and industry. However, the limited availability of suitable radionuclides has hampered widespread translation and application. In the present review,we discuss themost promising candidates for clinical application and the state of the art of their production and supply. In this review, along with 2 forthcoming reviews on chelation and clinical application of a-emitting radionuclides, The Journal of Nuclear Medicine will provide a comprehensive assessment of the field.

Keywords

211At; 212Pb/212Bi; 225Ac/213Bi; 227Th/223Ra; Production and supply of radionuclides; Targeted a-therapy

Disciplines

Nuclear | Radiochemistry

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