Award Date

1-1-1998

Degree Type

Thesis

Degree Name

Master of Science (MS)

Department

Biological Science

First Committee Member

Carl L. Reiber

Number of Pages

60

Abstract

I hypothesized that experimental elimination of blood flow via ligation of the conotruncus arteriosus would cause a cessation of blood vessel development and even vessel regression. India ink, injected to highlight the vasculature, had no effect on blood flow. Embryos were divided into ligated, sham, and control groups. After ligature placement and 6 hr. reincubation, KCl, added topically induced cardiac arrest. The diameters of the anterior cardinal vein, anterior vitelline vein, vitelline artery, and vitelline vein were not statistically different from sham and control values. Eye diameter increased equally in the presence and absence of blood flow. These results demonstrate that blood flow had no influence on vessel growth in diameter during a 6 hr. period. Blood flow did appear to offer a stabilizing influence against vessel degradation. A critical window of 6 hr. may exist during which the absence of blood flow has no detrimental effects on embryonic vasculature.

Keywords

Angiogenesis; Blood; Chick; Day; Embryo; Flow; Influence

Controlled Subject

Physiology

File Format

pdf

File Size

1884.16 KB

Degree Grantor

University of Nevada, Las Vegas

Language

English

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