Master of Public Health (MPH)
Environmental and Occupational Health
First Committee Member
Second Committee Member
Third Committee Member
Fourth Committee Member
Number of Pages
Albumin, a protein that when found in urine, is an early indicator of Chronic Kidney Disease (CKD). Genetic contributions have been shown to illustrate the gene-environment interactions that may lead to CKD in an individual; however, few studies have highlighted the interaction between responses of gene variations associated with the risk of increased albumin in young adults. This study’s purpose is to evaluate the hypothesis that candidate genes are related to microalbuminuria in young adults of the third wave of the National Longitudinal Study of Adolescent Health (Add Health Wave III). This longitudinal study includes an assessment of various candidate genes typically reported to be associated with behavioral differences in individuals and urinalysis results collected from a large population of young adults. The data set also contains a twin & sibling sample that is analyzed to find an association between various genes while controlling for family relativity. Findings include an association found within the sibling sample between women and single nucleotide polymorphisms (SNPs), rs892413 & rs4950. A better understanding of genetic factors associated with kidney functioning in this age group could improve our knowledge of the complex genetics of kidney function as well as guide prevention and intervention methods.
Stanford, Sabra, "Association of Genetic Factors with Chronic Kidney Disease in US Young Adults" (2017). UNLV Theses, Dissertations, Professional Papers, and Capstones. 3039.